Vascular Changes Associated With Endophthalmitis.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 71
- 试验地点
- 1
- 主要终点
- Best-Corrected Visual Acuity (BCVA)
研究概览
简要总结
This study aims to describe and investigate vascular changes associated with exogenous endophthalmitis, as well as to create a photo library where they are evidenced
详细描述
The implementation of multimodal imaging studies during the diagnosis and follow-up of patients with endophthalmitis may help identify, characterize, and differentiate between changes associated with host immune response, drug toxicity, or ischemia, thereby opening the possibility of implementing early treatments that lead to a better final prognosis. It is designed as a Prospective, Longitudinal, Observational, and Descriptive study. The population will be patients of the retina and vitreous service of Asociación para Evitar la Ceguera en México, who have a complete clinical record (age, sex, pathological personal history, non-pathological personal history, heredofamilial history, ophthalmologic history, allergies, medications, ophthalmologic examination with visual acuity, intraocular pressure at each visit), signed informed consent and with a history of exogenous or endogenous endophthalmitis with clear resolution criteria and clear means one week and one month after meeting the resolution criteria to be able to perform fluorescein angiography at both visits.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with a history of endophthalmitis Diagnosis of Endophthalmitis
- •Clinical symptoms: Pain, decrease in visual acuity, anterior chamber cells and/or vitreous turbidity, corneal edema, conjunctival hyperemia
- •Laboratory studies: B-mode USG and or positive culture
- •Patients who meet the endophthalmitis resolution criteria of the Mexican Endophthalmitis Study Group
- •Patients with previously signed informed consent
排除标准
- •Patients who have not signed the informed consent
- •Patients under 18 years.
- •Patients with endophthalmitis who do not meet the resolution criteria of the Mexican Endophthalmitis Study Group
结局指标
主要结局
Best-Corrected Visual Acuity (BCVA)
时间窗: The assessment will be performed at each visit (7 days and 1 month after meeting the inactivation criteria for endophthalmitis).
Best-Corrected Visual Acuity (BCVA) will be assessed according to the ETDRS guidelines. The test must be performed with the patient positioned 4 meters from the backlit panel, which must be calibrated to emit 85 cd/m². This procedure will be carried out by the retina fellow assigned to the case.
次要结局
- Fluorescein Angiography(The procedure may be performed at all study visits (7 days and 1 month after meeting the inactivation criteria for endophthalmitis).)
- Fundus Photography(The procedure may be performed at all study visits (7 days and 1 month after meeting the inactivation criteria for endophthalmitis).)