Retinal Vascular Changes After Endoscopic Endonasal Pituitary Surgery During One Year's Follow up, by Optical Coherence Tomography Angiography
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pituitary Adenoma
- Sponsor
- Federico II University
- Enrollment
- 14
- Locations
- 1
- Primary Endpoint
- Study of vessel density of the retinal vascular network in patients underwent endoscopic endonasal pituitary surgery, by optical coherence tomography angiography, during long-term follow up.
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
This study investigates the retinal vascular features, using optical coherence tomography angiography, in patients during one year's follow up after the endoscopic endonasal surgery to remove an intra-suprasellar pituitary adenoma compressing the optic nerve.
Detailed Description
The role of the optical coherence tomography angiography to detect the changes in retinal vascular networks in patients after 48 hours and 1 year from the endoscopic endonasal surgery to remove an intra-suprasellar pituitary adenoma compressing the optic nerve. The optical coherence tomography angiography allows a detailed and quantitative analysis of the retinal vascular networks and to follow their changes over time.
Investigators
Gilda Cennamo
Principal Investigator
Federico II University
Eligibility Criteria
Inclusion Criteria
- •age older than 45 years
- •diagnosis of pituitary adenoma
- •treatment-naive with endoscopic endonasal pituitary surgery
- •absence of other neurological disease
- •absence of vitreoretinal and vascular retinal diseases
Exclusion Criteria
- •age younger than 45 years
- •No diagnosis of pituitary adenoma
- •previous treatment with endoscopic endonasal pituitary surgery
- •presence of neurological disease
- •presence of vitreretinal and vascular retinal diseases
Outcomes
Primary Outcomes
Study of vessel density of the retinal vascular network in patients underwent endoscopic endonasal pituitary surgery, by optical coherence tomography angiography, during long-term follow up.
Time Frame: one year
To evaluate the changes in vessel density of the retinal vascular network 48 hours and 1 year after endoscopic endonasal pituitary surgery for the removal of an intra-suprasellar pituitary adenoma compressing the optic nerve, using optical coherence tomography angiography. The parameter analyzed by optical coherence tomography angiography was the vessel density of the retinal vascular network.