Early Retinal Vascular Modifications After Endoscopic Endonasal Pituitary Surgery: The Role of OCT- Angiography
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pituitary Adenoma
- Sponsor
- Federico II University
- Enrollment
- 14
- Locations
- 1
- Primary Endpoint
- Study of vessel density of the optic disc in patients underwent Endoscopic Endonasal Pituitary Surgery for the removal of an intra-suprasellar pituitary adenoma compressing the optic nerve.
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that received endoscopic endonasal approach for the removal of an intra-suprasellar pituitary adenoma compressing the optic nerve.
Detailed Description
To investigate the potential role of optical coherence tomography angiography in predicting the postoperative recovery of retinal vascular network of the optic disc in patients before and at 3 months after Endoscopic Endonasal Approach for the removal of an intra-suprasellar pituitary adenoma compressing the optic nerve. The optical coherence tomography angiography represents a novel and non-invasive diagnostic technique that allows a detailed analysis of retinal vascular features.
Investigators
Gilda Cennamo
Principal Investigator
Federico II University
Eligibility Criteria
Inclusion Criteria
- •age older than 45 years
- •diagnosis of pituitary adenoma
- •treatment-naïve with Endoscopic Endonasal Pituitary Surgery
- •absence of other neurological diseases
- •absence of vitreoretinal and vascular retinal diseases
Exclusion Criteria
- •age younger than 45 years
- •No diagnosis of pituitary adenoma
- •previous treatments with Endoscopic Endonasal Pituitary Surgery
- •presence of neurological diseases
- •presence of vitreoretinal and vascular retinal diseases
Outcomes
Primary Outcomes
Study of vessel density of the optic disc in patients underwent Endoscopic Endonasal Pituitary Surgery for the removal of an intra-suprasellar pituitary adenoma compressing the optic nerve.
Time Frame: 48 hours
To evaluate the role of optical coherence tomography angiography in predicting the recovery of the vessel density of the optic disc after surgery, using optical coherence tomography angiography (OCTA). The parameter analyzed by OCTA was the vessel density of the optic disc (percent)