Sucrose as a Preferred Carbohydrate in Sports Nutrition
试验速览
- 阶段
- 不适用
- 入组人数
- 17
- 试验地点
- 2
- 主要终点
- Exogenous carbohydrate oxidation rate (Part A)
研究概览
简要总结
Carbohydrates are an integral component of sports nutrition. Providing carbohydrate (CHO) during exercise delays the onset of fatigue and improves exercise performance by maintaining high rates of CHO oxidation. Traditionally, glucose, or glucose polymers have been the preferential CHO source found in sports drinks. However, during the intestinal absorption of large amounts of glucose (>1.2 g/min), sodium-dependent glucose transporters (SGLT1) may become fully saturated, potentially limiting the rate of exogenous CHO oxidation. In an effort to evade this limitation, research has suggested using multiple transportable carbohydrates in the composition of sports drinks. Multiple transportable carbohydrates are combinations of simple sugars that use different intestinal transporters during the absorption process. Ingesting multiple transportable carbohydrates may enhance the capacity for total intestinal CHO absorption, leading to an increase in the rate of exogenous CHO oxidation. Our purpose will be to examine the disaccharide sucrose in it's ability to provide exogenous fuel during and following prolonged exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years(Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •18 - 40 years of age
- •Endurance trained cyclist/triathlete
- •VO2 max ≥ 50 ml/kg/min
- •BMI < 25 kg/m2
排除标准
- •Use of medication
结局指标
主要结局
Exogenous carbohydrate oxidation rate (Part A)
时间窗: 180 min during trials 1-3
Carbohydrate oxidation as measured by breath samples
Endogenous carbohydrate oxidation (Part A)
时间窗: 180 min during trials 1-3
endogenous carbohydrate oxidation as measured through breath samples during trials 1-3
Glycogen utilization (Part B)
时间窗: 6 h post exercise during trials 4-6
Glycogen utilization measured through a muscle biopsy sample at post (\~90 min), 3 and 6 h post exercise. Part B; trials 4-6.
次要结局
- Indirect calorimetry (Part A)(every 30 min up to 180 min during trials 1-3)
- Plasma glucose(every 30 min up to 180 min during trials 1-6)
- Plasma insulin(every 30 minutes up to 180 min during trials 1-6)
