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临床试验/NCT00592891
NCT00592891Unknown1 期

Oxygen Toxicity Effects Using Los-Pressure Hyperbaric Oxygen Therapy in the Treatment of Chronic Brain Injury

Paul G. Harch, M.D.1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2002年4月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
1 期
发起方
入组人数
45
试验地点
1
主要终点
Oxygen toxicity

研究概览

简要总结

Hypothesis: That HBOT can be toxic in the low-pressure range.

详细描述

The study is a retrospective review of the author's experience treating chronic brain injury with HBOT, supplemented by cases communicated to the author, who developed untoward effects during or after their HBOT. The object of the study was to affirm or refute the author's general impression that there was an optimal dose of HBOT in chronic brain injury which was lower than the traditional dose applied in chronic non-central nervous system wounding. Furthermore, when this lower dosage range was exceeded and approached the traditional doses for non-CNS wounding oxygen toxicity would result. To address these impressions the study seeks to review the author's medical records and other patient/doctor communications to the author where side effects of HBOT occurred in the treatment of chronic brain injury and abstract signs, symptoms, and the dose of HBOT employed.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • Cerebral disorder of greater than one year's duration

排除标准

  • 未提供

研究组 & 干预措施

Hyperbaric oxygen therapy

Experimental

Patients undergoing low pressure HBOT for chronic brain injury

干预措施: Hyperbaric oxygen therapy (Drug)

结局指标

主要结局

Oxygen toxicity

时间窗: After completion of hyperbaric oxygen therapy

次要结局

未报告次要终点

研究者

发起方
Paul G. Harch, M.D.
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Paul G. Harch, M.D.

Clinical Professor of Medicine

Louisiana State University Health Sciences Center in New Orleans

研究点 (1)

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