Oxygen Toxicity Effects Using Los-Pressure Hyperbaric Oxygen Therapy in the Treatment of Chronic Brain Injury
试验速览
- 阶段
- 1 期
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Oxygen toxicity
研究概览
简要总结
Hypothesis: That HBOT can be toxic in the low-pressure range.
详细描述
The study is a retrospective review of the author's experience treating chronic brain injury with HBOT, supplemented by cases communicated to the author, who developed untoward effects during or after their HBOT. The object of the study was to affirm or refute the author's general impression that there was an optimal dose of HBOT in chronic brain injury which was lower than the traditional dose applied in chronic non-central nervous system wounding. Furthermore, when this lower dosage range was exceeded and approached the traditional doses for non-CNS wounding oxygen toxicity would result. To address these impressions the study seeks to review the author's medical records and other patient/doctor communications to the author where side effects of HBOT occurred in the treatment of chronic brain injury and abstract signs, symptoms, and the dose of HBOT employed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cerebral disorder of greater than one year's duration
排除标准
- 未提供
研究组 & 干预措施
Hyperbaric oxygen therapy
Patients undergoing low pressure HBOT for chronic brain injury
干预措施: Hyperbaric oxygen therapy (Drug)
结局指标
主要结局
Oxygen toxicity
时间窗: After completion of hyperbaric oxygen therapy
次要结局
未报告次要终点
研究者
Paul G. Harch, M.D.
Clinical Professor of Medicine
Louisiana State University Health Sciences Center in New Orleans
