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临床试验/NL-OMON24874
NL-OMON24874已完成不适用

Mitochondrial Coupling Efficiency, Respiration and Vitamin B2 status in Untrained and Endurance-trained Young Females

Wageningen University & Research0 个研究点目标入组 32 人开始时间: 待定最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
32

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

入选标准

  • 18-28 year old female
  • - BMI 18.5-25 kg/m2
  • - VO2max = 37 mL/kg/min or VO2max = 47 mL/kg/min;
  • - Performed a valid VO2max test In order for the test to be considered valid two out of three of the following conditions should be met:
  • 1) The maximal heart rate is within 10 beats of the predicted maximum (220 – age)
  • 2) A plateau in in VO2 was reached; VO2 fails to increase with 150 mL/min, despite an increase in work load
  • 3) Respiratory exchange ratio (RER) = 1.00 has been achieved

排除标准

  • Health concerns regarding respiratory and pulmonary diseases, for example COPD or (exercise induced) asthma
  • (Known symptoms of) chronic diseases, for example cardiovascular disease and cancer;
  • (Known symptoms of) metabolic diseases, for example type I or II diabetes or hyperthyroidism;
  • (Known symptoms of) inborn metabolic diseases, for example glucose-6-phosphate dehydrogenase (G6PD) deficiency;
  • (Known symptoms of) hematological disorders, for example anemia or disturbed red blood cell formation;
  • Haemoglobin concentrations below 7.5 mmol/L;
  • Regular smoker (defined as smoking >5 cigarettes per week);
  • Lactating or pregnant;
  • Following a veganistic lifestyle, i.e. excluding the consumption of animal or animal-derived food products. Vegetarians are allowed to participate in the study.
  • Usage of hormonal contraceptive medications other than the birth control pill Microgynon 20/30 or a generic variant containing 0.02/0.03 mg ethinylestradiol and 0.10/0.15 mg levonorgestel. Examples include IUD contraceptives or contraceptive rings. The use of condoms or pessaria is allowed;
  • Recent use (within four months) of supplements with suggestive training effects, for example creatine phosphate, EPO or anabolic steroid;
  • Recent daily usage (within four weeks) of supplements containing vitamin B2 (including multivitamin supplements) and usage of vitamin B2 supplements during the study;
  • Usage of recreational drugs, for example marihuana, amphetamines and cocaine during the study (starting after first screening day);
  • Suffers from (sport) injury that hampers maximal exercise performance;
  • Blood donation during the previous 2 months or during the course of study;
  • Current participation in other clinical trials;
  • Not subscribed to a general practitioner (GP) practice;
  • Employed or undertaking a thesis or internship at the department of Human and Animal Physiology.

研究者

发起方
Wageningen University & Research

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