NL-OMON47816已完成不适用
Cardiac mitochondrial function; Comparison of in and ex vivo measurements - 31P-MRS study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Patients undergoing elective valve replacement or cardiopulmonal bypass surgery
- •- Gender: male or male
- •- The patients should be aged 40-75 years
- •- The type 2 diabetic patients should be obese (BMI > 27 kg/m2) and non-insulin dependent
- •- The obese controls should be BMI matched with the diabetic patients (BMI > 27 kg/m2)
- •- The lean subjects should have a normal BMI (20-25 kg/m2)
排除标准
- •- Insulin dependent diabetic subjects.
- •- Patients with instable angina or heamodynamically instable patients
- •- Use of Thiazolidines (glitazone/rosiglitazone/pioglitazone/troglitazone)
- •- Weight gain/loss > 3 kg in the last 6 months or signs of cachexia
- •- Contraindications for MRI scans.
研究者
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