Role of blood cell mitochondria in heart failure

Not Applicable

Completed

• Conditions: Heart failure

• Registration Number: JPRN-UMIN000022564
• Lead Sponsor: Hokkaido University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-06-02
• Study Completion: 2020-03-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up continuing
• Sex: All
• Target Recruitment: 83

Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients with active inflammation 2)Patients with malignant tumor 3)Patients who are receiving steroid or immunosuppressant

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mitochondrial respiratory capacity in blood cells

Secondary Outcome Measures

Name	Time	Method
1)Mitochondrial oxidative stress originated from blood cells 2)Systemic inflammatory biomarkers 3)Systemic oxidative stress 4)Gene expression and protein synthesis regarding mitochondrial function, mitochondrial biogenesis, morphology, and inflammatory cytokines 5)Mitochondrial density in blood cells 6)Events (all-cause death, cardiac death, all-cause hospitalization, and hospitalization for worsening heart failure)