Intestinal Perforation in Patients Receiving an Orthtopic Liver Transplantation in the Montpellier University Hospital: a Retrospective and Observational Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Evaluate the total length of stay
研究概览
简要总结
Liver transplantation enhances the prognosis of patients with cirrhoses or hepatocellular carcinoma. However some patients develop intestinal perforations for which the prognosis is poor.
The aim of the study is to evaluate the risk factors of intestinal perforations using a retrospective study scheme.
详细描述
Liver transplantation enhances the prognosis of patients with cirrhoses or hepatocellular carcinoma. However some patients develop intestinal perforations for which the prognosis is poor.
The aim of the study is to evaluate the risk factors of intestinal perforations using a retrospective study scheme. Previous studies have shown a possible implication of drugs or medical history or intraoperative complications. The investigators aim to describe the other possible risk factors (such as portal vein clampage) and the type of surgery done after the diagnosis and its impact on survival as well.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients having received an orthotopic liver transplantation in the Montpellier University Hospital from 2014 to 2019
- •for the group Perforation: patients having during the follow-up a complication such as intestinal perforation. The complete list uses the ICD-10 codes for intestinal perforation, esophageal perforation, duodenal perforation etc.
排除标准
- •No exclusion criteria
结局指标
主要结局
Evaluate the total length of stay
时间窗: 6 months.
Evaluate the total length of stay
次要结局
- Evaluate the number of perforations(1 month, 3 months, 6 months.)
- Evaluate the occurrence of an acute or chronic rejection(1 month, 3 months, 6 months.)
- Evaluate the occurrence of death(1 month, 3 months, 6 months.)
- Evaluate the quality of life(1 month, 3 months, 6 months.)
- Evaluate the total number of complications(1 month, 3 months, 6 months.)