NCT07133360已完成不适用
Cocktail of Vitamin B, Vitamin D and Melatonine VS Ibuprofen in the Surgical Third Molar Extraction. Randomized Clinical Trial
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Swelling
研究概览
简要总结
Combination of vitamins and melatonine compared with the conventional use of ibuprofen after surgical third molar extraction
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers, non ibuprofen allergic, presence of impacted lower third molar
排除标准
- •Diseases that avoid surgical intervention
研究组 & 干预措施
Ibuprofen 400
Active Comparator
Three ibuprofen 400 doses
干预措施: Third molar extraction (Procedure)
Coctail mixed Drugs
Experimental
Vitamin D, Vitamin B and Melatonine at night instead Ibuprofen
干预措施: Third molar extraction (Procedure)
结局指标
主要结局
Swelling
时间窗: 7 DAYS
Face measurement for swelling
Trismus
时间窗: 7 DAYS
Opening limitation
Post operative pain
时间窗: 10 DAYS
VAS pain scale
次要结局
- Inflammatory profile(7 days)
- Rescue analgesia(7 DAYS)
研究者
Jesús Torres García Denche
Doctor
Universidad Complutense de Madrid
研究点 (1)
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