NCT07075874招募中不适用
Preoperative Neutrophil-to-Lymphocyte Ratio as a Predictor of Post-Dural Puncture Headache Following Cesarean Section Under Spinal Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 821
- 试验地点
- 1
- 主要终点
- Postdural Puncture Headache (PDPH) incidence
研究概览
简要总结
This study will aim to investigate whether systemic inflammatory markers-especially the neutrophil-to-lymphocyte ratio (NLR)-obtained from preoperative complete blood counts can predict the development of post-dural puncture headache (PDPH) in obstetric patients undergoing cesarean section under spinal anesthesia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women aged 18 years or older
- •Underwent elective or emergency cesarean section under spinal anesthesia
- •Had complete preoperative complete blood count (CBC) data available
- •No known hematological or inflammatory disease
- •No intraoperative complications recorded
- •Medical records accessible for postoperative follow-up regarding PDPH symptoms
排除标准
- •Age under 18
- •Absence of preoperative complete blood count data
- •Presence of hematologic malignancy, active infection, autoimmune disease, or immunosuppressive therapy
- •Platelet count <150,000/mm³ or INR >1.5
- •Incomplete or missing medical records
结局指标
主要结局
Postdural Puncture Headache (PDPH) incidence
时间窗: Within 10 days postoperatively
The occurrence of PDPH symptoms within 10 days following spinal anesthesia in obstetric patients, as documented in medical records.
次要结局
未报告次要终点
研究者
İlke Dolgun
Assoc. prof
Haseki Training and Research Hospital
研究点 (1)
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