Analgesic Efficacy of Opioid-Free Anesthesia Protocol Combined With Ultrasound-Guided External Oblique Intercostal Plane Block for Laparoscopic Cholecystectomy: A Prospective Randomized Comparative Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 70
- 主要终点
- the amount of fentanyl consumption used for pain relief in the first six hours after laparoscopic cholecystectomy (LC) under general anesthesia
研究概览
简要总结
laparoscopic cholecystectomy (LC) is often accompanied by moderate-to-severe postoperative pain. opioid-free anesthesia (OFA) consists of a variety of non-opioid narcotic drugs and techniques.
详细描述
opioid-free anesthesia (OFA) can control postoperative pain effectively and reduce opioid drug consumption.
The external oblique intercostal plane (EOI) block is easy to perform and may provide effective analgesia for laparoscopic cholecystectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients scheduled for elective laparoscopic cholecystectomy (LC) surgery under general anesthesia, American Society of Anesthesiologists (ASA) physical status I-II, aged from 18 to 65 years old of either sex
排除标准
- •Contraindications to regional block (coagulopathy, infection at the needle insertion site, or known allergy to amide local anesthetics)
- •Pregnancy or breastfeeding women
- •Body mass index (BMI) > 35 Kg/m2
- •History of hepatic, renal, or cardiac disease
- •Chronic opioid use, or history of chronic pain (pain present for more than 6 months)
- •Thoracic deformity
- •Neuropsychiatric disorders
- •Patient refusal.
研究组 & 干预措施
Group I
Patients will receive ultrasound-guided external oblique intercostal plane (EOI) block added to an opioid-free anesthesia (OFA) protocol
干预措施: EOI with OFA (Procedure)
Group II
Patients will receive an opioid-free anesthesia (OFA) protocol
干预措施: OFA (Drug)
结局指标
主要结局
the amount of fentanyl consumption used for pain relief in the first six hours after laparoscopic cholecystectomy (LC) under general anesthesia
时间窗: The first six hours after surgery
Assessed in microgram
次要结局
未报告次要终点
研究者
Seham Mohamed Moeen Ibrahim
Assiut University
Assiut University