NCT05325580招募中3 期
Intravenous Magnesium Sulfate Vs Placebo to Treat Non-traumatic Acute Headaches in the Emergency Department
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 424
- 试验地点
- 1
- 主要终点
- Intravenous Magnesium Sulfate to Treat Non -Traumatic Acute Headaches in the Emergency Department
研究概览
简要总结
Intravenous Magnesium Sulfate Vs Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department
详细描述
Rate of Intravenous Magnesium Sulfate Vs Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •informed consent
- •age >18 years
- •Acute non-traumatic acute headaches
- •patients treated in ED
- •Magnesium sulfate and aspirin administered intravenously (IV)
排除标准
- •Current regular use of analgesics, anticonvulsants or antidepressants
- •Renal disorder with a low glomerular filtration rate (<60 ml/min)
- •Neuromuscular disorder
- •Pregnant woman
- •Contrindication
- •Allergy to NSAID
- •Traumatic Headache
- •Chronic headache ( headache occurring at least 15 days per month for at least 3 months)
- •Hemodynamic instability
研究组 & 干预措施
Placebo Group
Placebo Comparator
1g paracetamol + 20 min infusion of 150ml of saline serum
干预措施: Magnesium sulfate (Drug)
magnesium group
Experimental
1g paracetamol + 20 min infusion of 2g magnesium in 150 ml of serum saline
干预措施: Magnesium sulfate (Drug)
结局指标
主要结局
Intravenous Magnesium Sulfate to Treat Non -Traumatic Acute Headaches in the Emergency Department
时间窗: 1day
Patients with Non -Traumatic Acute Headaches in the Emergency Department recived 1g paracetamol + 20 min infusion of 2g magnesium
次要结局
- Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department(1 day)
研究者
Pr. Semir Nouira
Pr.Semir Nouira chef of emergency deparment
University of Monastir
研究点 (1)
Loading locations...
相似试验
撤回
2 期
MgSO4 vs Metoclopramide for Headache in Pregnant WomenHeadacheNCT00632606Women and Infants Hospital of Rhode Island
Unknown
不适用
The effect of intravenous Magnesium Sulfate versus an analgesic on the duration of Spinal anesthesia and post-operative pain in patients with leg fracture.leg fracture.Multiple fractures of lower legIRCT2016022126685N1Ahvaz Jundishapur University Of Medical Sciences, Ahvaz, Iran70
尚未招募
4 期
Magnesium sulphate vs Dexmedetomedine for Blood Pressure control in laparoscopic cholecystectomy.CTRI/2024/02/063248Goa Medical College
招募中
Unknown
Comparison of intravenous Magnesium Sulphate combined with Acetaminophen versus intravenous Nalbuphine in COPD patients undergoing elective CholecystectomyAnalgesic efficacy of Non opioid Anaesthesia (NOA).Family history of Asthma and other Chronic lower respiratory diseasesZ82.5IRCT20230819059186N2Combined Military Hospital Rawalpindi Pakistan110
已完成
2 期
Effects of magnesium sulfate in prevention of shivering during spinal anesthesia in cesarean sectioSpinal anesthesia.Other complications of spinal and epidural anaesthesia during pregnancyIRCT201308254780N4Vice Chancellor for Research, Mashhad University of Medical Science80