Clinical Implication of Prolonged Vasospasm in Subarachnoid Hemorrhage
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 109
- 主要终点
- Clinical implication
研究概览
简要总结
The prevalence and clinical implications of prolonged cerebral vasospasm in patients with subarachnoid hemorrhage are unknown.
详细描述
The prevalence and clinical importance of prolonged cerebral vasospasm (after day 21 of bleeding) in patients with subarachnoid hemorrhage is unknown.
Objectives: To determine the prevalence and clinical relevance of prolonged vasospasm in patients with subarachnoid hemorrhage secondary to cerebral aneurysm.
A prospective and observational study was conducted. Adult patients with a diagnosis of subarcnoid hemorrhage CT scan or presence of blood in the cerebrospinal fluid were incorporated. Patients with vasospasm were followed daily with transcranial doppler. Those with technical impossibility to perform transcranial and pregnant Doppler were excluded. Day 0 was defined, the day of the last bleeding.
Evaluation: 1) It was considered in patients with prolonged vasospasm: whether or not it was associated with clinical manifestation (deterioration of the sensory or new neurological deficit) and 2) the magnitude of the vasospasm (mild, moderate or severe) was measured by transcranial doppler.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subarachnoid hemorrhage -
排除标准
- 未提供
结局指标
主要结局
Clinical implication
时间窗: 1 month
Presence or not of neurological symptoms related to intracranial vasospasm (delayed cerebral ischemia)
Gravity of vasospasm by transcranial doppler
时间窗: 1 month
Mild, moderate and severe according to Aaslid scale
次要结局
- Mortality assessment(six monts)
研究者
Nestor Pistillo
Head of Intensive Care Unit at Hospital El Cruce
Hospital El Cruce