Comparison of Ultrasound-Guided Quadratus Lumborum Block and Epidural Analgesia for Postoperative Pain Management After Renal Transplantation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Morphine consumption
研究概览
简要总结
Quadratus lumborum block as an alternative for postoperative analgesia compared with epidural block
详细描述
Epidural analgesia is the main choice of analgesia following kidney transplant surgery. However, continuous epidural technique had some concerning side effects such as hemodynamic instabilities, urine retention, motor/sensory disturbances/weakness, and mobilisation comfort, it could also cause hypotension which could affect graft success. Quadratus lumborum (QL) block had lesser side effects thus could be an option for postoperative analgesia, however there are no study showing the safety and success rate of QL block techniques for patients who underwent kidney transplant surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients undergoing elective kidney transplant laparotomy surgery
- •Agrees to participate in research
- •BMI < 30 kg/m2
排除标准
- •Declines to participate in research
- •Contraindications to intervention procedures (epidural or quadratus lumborum block)
- •History of local anaesthetic allergy
- •Systemic allergic reactions, anaphylactic reaction, cardiac arrest
- •Failure of intervention procedures (epidural or quadratus lumborum block)
- •Intraoperative complications (massive bleeding, hypotension)
结局指标
主要结局
Morphine consumption
时间窗: 24 hours
Additional analgesia required at 2, 6, 12, and 24 hours after surgery
次要结局
- Blood ropivacaine level(24 hours)
- Urine output(24 hours)
- Total minimum and maximum dose of vasoactive agents(24 hours)
- First time morphine required(24 hours)
- Bromage score(24 hours)
- Ramsay score(24 hours)
- Dermatomal coverage of analgesia procedure(Immediately after anaesthesia completion)
- Pain Intensity(24 hours)
研究者
Dita Aditianingsih
Principal investigator, Anesthesiologist Consultant
Indonesia University