Brain and Genetic Predictors of Individual Differences in Pain and Analgesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 541
- 试验地点
- 1
- 主要终点
- Pain Rating Scores Made on a Visual Analog Scale (VAS)
研究概览
简要总结
The purpose of the study is to gain a better understanding of pain processing in the brain. Our understanding of how pain is processed in the brain is limited. We are testing for individual differences in pain perception and emotion.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participants must be registered in the Colorado Community Twin Sample (CTS).
排除标准
- •Not being registered in the Colorado Community Twin Sample (CTS).
- •Any MRI contraindications.
结局指标
主要结局
Pain Rating Scores Made on a Visual Analog Scale (VAS)
时间窗: Measured during pain tasks at a single 4 hour experimental session (within one month of screening completion).
Self reported pain using a Visual Analogue Scale (VAS) ranging from 0-100 (with 0 representing "no pain at all" and 100 representing "most intense pain imaginable (in the context of the experiment)). Higher scores indicate more pain. 0 is the minimum value and 100 is the maximum value. This scale is used for both thermal and mechanical pain. Reported values reflect averages of VAS ratings for individual stimuli for each of thermal and mechanical pain.
次要结局
未报告次要终点
研究者
Tor Wager
Director, Cognitive and Affective Neuroscience Laboratory; Professor, Department of Psychology and Neuroscience and the Institute for Cognitive Science
University of Colorado, Boulder