Comparing Different Methods For Measurement of Cardiac Output During Orthotopic Liver Transplantation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Agreement between cardiac output measurements obtained with PAC, Vigileo and LiDCO
研究概览
简要总结
The purpose of the study is to determine if the less invasive monitors are as reliable for measuring heart function in patients undergoing liver transplantation as the more invasive pulmonary artery.
详细描述
Pulmonary artery catheter (PAC)is considered the gold standard in monitoring of heart function during orthotopic liver transplantation (OLT). Placement of PAC is very invasive (it passes thorough the heart chambers and into the pulmonary artery) and its benefits on the outcomes have not been proven. This study compares two newer FDA approved much less invasive devices to the PAC. The two new devices assess the heart function based either on the peripheral arterial waveform alone (Vigileo, Edwards Lifesciences)or the combination of peripheral arterial waveform and chemical indicator dilution (LiDCO, Cambridge, UK).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients over 18 years of age
- •Scheduled for liver transplantation
- •Patient undergoing vascular surgery where invasive arterial pressure is indicated (control subjects)
排除标准
- •We will exclude patients taking lithium based medication
- •Patients who weigh less than 40 kg; AND
- •Patients who are pregnant
结局指标
主要结局
Agreement between cardiac output measurements obtained with PAC, Vigileo and LiDCO
时间窗: Specific phases of liver transplantation surgery
次要结局
未报告次要终点