Effect of Low Intensity Blood Flow Restriction Training on Lower Extremity Strength and Hypertrophy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 2
- 主要终点
- One Repetition Maximum
研究概览
简要总结
The particpant will complete baseline testing by measuring subjects' quadriceps muscle thickness (cm) via ultrasound technology, as well as have them complete a one repetition maximum (1RM) test on the leg press machine and an isometric knee extension using a dynamometer - strength measures will be calculated for both right and left legs. After baseline testing, subjects will complete 6 weeks of the testing protocol that will consist of leg press exercises at 30% of their 1RM. Subjects will be randomized to either wear a cuff that partially restricts blood flow to the limb (Study Group), or to wear a cuff that does not restrict blood flow (Control Group). Exercises will be completed 2x/week and will take approximately 10 total minutes (5 for warm up, 5 for testing protocol) per session. After 6 weeks, muscle thickness, leg press 1RM, and quadriceps extension strength will be re-tested and compared to the initial measurements.
详细描述
Session 1 - baseline testing
- 5-minute warm-up; 1RM calculation for both right and left legs using a supine leg press machine; isometric quadriceps strength measurement using a dynamometer; muscle thickness measurements of both right and left quadriceps muscle using ultrasound technology.
- After day 1 testing; randomly allocate subjects to either control group or experimental group
Sessions 2-13 - 6 weeks of exercise protocol, 2x/per week
Both the experimental and control groups will complete the same protocol for the entirety of the study:
- 5- minute warm up
- Using a single-leg press exercise machine: Subjects complete the testing protocol with either partial blood flow restriction (cuff inflated to 100-250 mmhg depending on size of person) or no blood flow restriction (placebo inflation) on right limb.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 49 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-49
排除标准
- •Hypertensive
- •Recent back or lower extremity injury
- •History of blood clotting
- •Varicose veins
- •Adults lacking the capacity to consent for themselves
结局指标
主要结局
One Repetition Maximum
时间窗: 6 weeks
One repetition maximum on the single leg press. Isometric quadriceps extension strength.
次要结局
- Quadriceps Muscle Thickness(6 weeks)