Novel Functional Medicine Intervention With Cognitive Training for Mild Cognitive Impairment (MCI): A Multiple Baseline Study Across Cases
试验速览
- 阶段
- 不适用
- 入组人数
- 5
- 试验地点
- 2
- 主要终点
- Evidence of overall cognitive function improvement
研究概览
简要总结
The purpose of this investigation is to conduct a series of case studies on the impact of a novel functional medicine approach to improving cognitive skills, brain structure, and daily functioning for participants with Mild Cognitive Impairment (MCI).
详细描述
Using a multiple baseline design across cases with start point randomization, the proposed study will examine the outcomes from a combination of optimized diet, exercise, nutritional supplements, and cognitive training across domains on standardized measures used to monitor treatment effectiveness for Mild Cognitive Impairment (MCI).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 50+ previously diagnosed with MCI
- •Living in the greater Colorado Springs area
排除标准
- •No braces, metal implants, or claustrophobia that would contraindicate magnetic resonance imaging
结局指标
主要结局
Evidence of overall cognitive function improvement
时间窗: within 14 days after completing the intervention
Confirmed by change in pretest to post-test scores on the Dementia Rating Scale (DRS-2)
次要结局
- Evidence of change in brain function(within 30 days after completing the intervention)
- Evidence of improvement in executive function(within 14 days after completing the intervention)
- Evidence of improvement in cognitive flexibility(within 14 days after completing the intervention)
- Evidence of improvement in auditory attention(with 14 days after completing the intervention)
- Evidence of improvement in visual attention(with 14 days after completing the intervention)