NCT07182136已完成不适用
The Impact of Hepatic Steatosis on Survival After Pancreaticoduodenectomy for Resectable Pancreatic Cancer. A Multifactorial Analysis of Metabolic Dysfunction
Wei-Hsun Lu0 个研究点目标入组 200 人开始时间: 2015年1月1日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 主要终点
- Incidence of postoperative nonalcoholic fatty liver disease (NAFLD)
研究概览
简要总结
We will use simple summaries, educational handouts, and discussions with doctors and nurses to explain this study. The study looks at patients with early-stage pancreatic cancer who undergo pancreaticoduodenectomy (Whipple surgery). We found that some patients develop fatty liver (non-alcoholic fatty liver disease, NAFLD) within six months after surgery, which can affect nutrition, blood sugar control, and long-term survival.
To help patients and families understand, we will:
- Provide clear written information sheets about the purpose of the study and its findings.
- Use diagrams or plain-language explanations of terms like "pancreatic exocrine function" and "fatty liver."
- Share results with healthcare providers so they can guide patients in nutrition, enzyme replacement, diabetes monitoring, and follow-up care.
- Offer contact information for the research team to answer questions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults with stage I-II pancreatic ductal adenocarcinoma.
- •Underwent curative-intent pancreaticoduodenectomy (conventional or pylorus-preserving).
- •Surgery between January 2015 and May
- •Complete clinical and imaging data available.
- •Survived at least 6 months postoperatively.
排除标准
- •Preoperative hepatic steatosis
- •Incomplete clinical or imaging data
- •Death within 6 months after surgery
结局指标
主要结局
Incidence of postoperative nonalcoholic fatty liver disease (NAFLD)
时间窗: 6 months after pancreaticoduodenectomy
次要结局
未报告次要终点
研究者
Wei-Hsun Lu
MD
National Cheng Kung University
相似试验
Unknown
不适用
A Hepatitis B With Hepatic Steatosis StudyHepatitis B, ChronicHepatic SteatosisNCT02392598Fatty Liver and Alcoholic Liver Disease Study Group, China3,000
已完成
不适用
Hepatic Steatosis and Chronic Hepatitis B VirusChronic HepatitisNCT05678582Sohag University91
招募中
不适用
An Observational Study Evaluating Patients With Chronic Liver Diseases Associated With Hepatic SteatosisChronic Liver DiseaseNCT05335603University of Copenhagen335
招募中
不适用
Hepatic Safety of Statin Use in Neurology InpatientsStatin Adverse ReactionNCT06592196Shanghai Yueyang Integrated Medicine Hospital2,000
已完成
不适用
Hepatic Artery Stenosis and Thrombosis After Liver Transplantation in ChildrenHepatic Artery ThrombosisHepatic Artery StenosisPediatric ALLLiver Transplant ComplicationsNCT05818644University Medical Center Groningen583
