Investigation of the Relationship Between Motor Imagery, Body Awareness, Kinesiophobia, Physical Activity, Symptom Severity, and Physical Frailty in Patients With Parkinson's Disease
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Vividness of Movement Imagery Questionnaire-2 (VMIQ-2) Total and Subscale Scores
研究概览
简要总结
The aim of this study is to examine the associations between motor imagery capacity, body awareness (interoceptive awareness), kinesiophobia, physical activity level, and symptom severity in individuals with Parkinson's disease. In addition, the study aims to evaluate the relationships between these variables and physical frailty. This cross-sectional observational study will provide insight into the biopsychosocial factors associated with frailty in Parkinson's disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinically diagnosed Parkinson's disease
- •Hoehn and Yahr stage 1-3
- •Age 40 to 85 years
- •Mini-Mental State Examination (MMSE) score ≥24
- •Attending the Movement Disorders Outpatient Clinic, Department of Neurology
- •Able to understand the study procedures and provide written informed consent
排除标准
- •Major depressive disorder or psychotic disorder
- •Advanced dementia
- •Severe cardiovascular or respiratory disease
- •Uncontrolled chronic systemic disease (e.g., diabetes mellitus or hypertension)
- •Additional neurological or orthopedic conditions that may affect assessment performance
- •Severe visual or hearing impairment that could interfere with study assessments
- •Inability to cooperate with the physiotherapist during study assessments
结局指标
主要结局
Vividness of Movement Imagery Questionnaire-2 (VMIQ-2) Total and Subscale Scores
时间窗: Baseline (at the time of questionnaire administration)
Motor imagery ability will be assessed using the Vividness of Movement Imagery Questionnaire-2 (VMIQ-2), a validated self-report instrument with established Turkish validity and reliability. The questionnaire consists of 12 items assessing the vividness of imagined movements across three domains: external visual imagery, internal visual imagery, and kinesthetic imagery. Each item is rated on a 5-point Likert scale (1-5), and separate scores are calculated for each subscale as well as a total score. Total scores range from 17 to 68, with higher scores indicating lower vividness of motor imagery ability. Assessments will be administered jointly by the responsible physician and a physiotherapist.
Multidimensional Assessment of Interoceptive Awareness-2 (MAIA-2) Total and Subscale Scores
时间窗: Baseline (at the time of questionnaire administration)
Interoceptive body awareness will be assessed using the Multidimensional Assessment of Interoceptive Awareness-2 (MAIA-2), a validated self-report instrument with established Turkish validity and reliability. The Turkish version consists of 34 items across seven subscales: Noticing, Not-Distracting, Attention Regulation, Emotional Awareness, Self-Regulation, Body Listening, and Trusting. Each item is rated on a 6-point Likert scale ranging from 0 (never) to 5 (always). Subscale scores are calculated separately, with higher scores indicating greater interoceptive body awareness in the respective domain.
Fried Frailty Phenotype (FFP) Classification and Total Criteria Score
时间窗: Baseline (at the time of physical and questionnaire-based assessment)
Physical frailty will be assessed using the Fried Frailty Phenotype (FFP), a validated measure based on five criteria: unintentional weight loss, exhaustion, low physical activity, weak handgrip strength, and slow walking speed. Participants will be classified as robust (0 criteria), prefrail (1-2 criteria), or frail (≥3 criteria). Each criterion will be scored as present or absent, and a total score ranging from 0 to 5 will be calculated. In addition to the original criteria, population-specific cut-off values for handgrip strength (≤13.6 kg for women and ≤27.7 kg for men) will be applied. Higher scores indicate greater frailty.
次要结局
- Tampa Scale for Kinesiophobia (TSK) Total Score(Baseline (at the time of questionnaire administration))
- Physical Activity Scale for the Elderly (PASE) Total Score(Baseline (reflecting physical activity over the previous 7 days))
- Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Total Score(Baseline (at the time of clinical assessment))
研究者
Nuray Alaca
Assoc. Prof. Nuray Alaca
Acibadem University