Pulmonary Prehabilitation With Incentive Spirometry in Patients Undergoing One-Lung Ventilation and the Effect on Postoperative Lung Function: A Randomized-Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 23
- 试验地点
- 2
- 主要终点
- Lung Volumes
研究概览
简要总结
Postoperative pulmonary complications (PPCs) are the most common complication following thoracic surgery. PPCs are associated with prolonged hospital stay, increased morbidity, mortality, ICU admission, and healthcare costs (Azhar, 2015). Current preoperative optimization in this patient group includes smoking cessation and management of Chronic Obstructive Pulmonary Disease with inhaled bronchodilators and inhaled steroids as indicated. There have been studies using preoperative incentive spirometry in patients undergoing laparotomy with conflicting results, but scant data on its use in patients undergoing one-lung ventilation (Tyson, et al., 2015; Cattano, et al., 2010). A study from 2013 investigated the effectiveness of incentive spirometry in patients following thoracotomy and found conflicting results, without significant improvement in lung function or reduction in PPCs, but a larger difference in frequency of PPC was noted, indicating possible benefit to intervention and a need for further study (Agostini, et al., 2013). Volume-based incentive spirometry pre- and postoperatively has also been found to improve pulmonary function and diaphragm excursion in patients undergoing laparoscopic surgery (Alaparthi, et al., 2016).
Patients customarily receive an incentive spirometer for use postoperatively in the PACU. There is scant data in the thoracic surgery population concerning prehabilitation by dispensing the incentive spirometer at the PACT evaluation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for thoracic surgery procedures involving one-lung ventilation
- •open thoracotomy
- •Video-assisted thoracoscopic surgery (VATS)
- •Robotic-assisted thoracoscopic surgery (RATS)
- •Procedures to include: Lung resection for any purpose, esophagectomy, thymectomy
- •Patients undergoing esophagectomy performed by a general surgeon
- •Patients willing and able to independently perform incentive spirometry
排除标准
- •Trauma patients
- •Lung Volume reduction surgery (LVRS)
- •In-Patients
- •Patients not undergoing one-lung ventilation
- •Patients undergoing thoracoabdominal aortic aneurysm repair
- •Transhiatal esophagectomy (does not involve one-lung ventilation)
- •Lung transplantation
结局指标
主要结局
Lung Volumes
时间窗: From the time of admission to the pre-operative holding area to 72 hours post-operatively
Mean Lung Volumes
次要结局
未报告次要终点
研究者
Jeffry B. Dobyns
Principal Investigator
University of Alabama at Birmingham
