NCT04268381已完成不适用
Local And Systemic Levels of aMMP-8 in Gingivitis and Stage 3 Periodontitis
Aydin Adnan Menderes University1 个研究点 分布在 1 个国家目标入组 83 人开始时间: 2020年1月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 83
- 试验地点
- 1
- 主要终点
- Oral (GCF and saliva) and serum levels of aMMP-8 in periodontitis and gingivitis
研究概览
简要总结
Periodontal disease is an inflammatory process that can result in tooth loss and also is considered a modifying factor for systemic health. Matrix metalloproteinase (MMP)-8 is the major collagenase of periodontal tissue breakdown. The aim of the present study is to analyze active (aMMP-8) levels in gingival crevicular fluid (GCF), saliva and serum in the context of new criteria of gingivitis and stage 3 grade C periodontitis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 25 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •systemically healthy and non-smoker individuals aged 25 to 50 years
- •having ≥20 teeth present (except third molars)
- •individuals with periodontally healthy, gingivitis and stage 3 periodontitis diagnoses
排除标准
- •having any systemic disease
- •pregnancy or lactation
- •using antibiotic or any anti-inflammatory drug or any periodontal treatment within the past 6 months.
结局指标
主要结局
Oral (GCF and saliva) and serum levels of aMMP-8 in periodontitis and gingivitis
时间窗: through study completion, an average of 4 months
aMMP-8 levels
次要结局
未报告次要终点
研究者
Zeynep Pinar KELES YUCEL
Assistant Prof.
Giresun University
研究点 (1)
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