NCT03013621Unknown不适用
Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative (COVD)
University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2017年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Quantification of sonographic markers of right ventricular
研究概览
简要总结
Acute renal failure (ARF) is a frequent complication in the postoperative cardiac surgery, and is a major risk factor for mortality in this context.
The right ventricular dysfunction post cardiopulmonary bypass (CPB) is also a common complication, close to 100% if one takes into account the transient dysfunction.
A recent study showed that right ventricular dysfunction and the IRA seemed related, rather on the slope of venous congestion. We wish to study this phenomenon more specifically in particular to offer reliable diagnostic markers of venous congestion.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: all major patient
- •Gender: both
- •Subject has signed an informed consent
- •IRA KDIGO stage 1 or urine output <0.5 mL / kg / h for at least 6 hours / elevation creat> 26.5μmol / L
- •Patient in sinus rhythm at the time of the ultrasound measurements
- •No diuretic since intervention
- •Absence of circulatory failure (low doses of catecholamines tolerated)
- •Extubated: absence of mechanical ventilation
排除标准
- •Chronic heart failure right
- •Chronic renal failure (GFR <60)
- •Usual treatment with high dose diuretics (furosemide> 40mg / day)
- •Endocarditis
- •Emergency surgery (aortic dissection, emergency bypass surgery) / heart surgery D / redux
- •Circulatory Support
- •ACFA / electro-paced rhythm
- •Inability to give informed about information (subject in emergencies, understanding of the subject of difficulty, ...)
- •Topic under judicial protection
- •Topic guardianship or curatorship
- •Pregnancy (women of childbearing age)
- •Breastfeeding
结局指标
主要结局
Quantification of sonographic markers of right ventricular
时间窗: 1 hour after cardiac surgery
次要结局
未报告次要终点
研究者
研究点 (1)
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