Active Cue-Training in Neglect
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
- 试验地点
- 2
- 主要终点
- Change in word and word-part omissions in standardized reading of text and word list
研究概览
简要总结
The presented study investigates standardized visual cueing in reading and visual spatial task as a treatment method for spatial neglect. In a randomized controlled design patients receive either cued reading and visual spatial tasks (intervention) or treatment which is unspecific to neglect (control).
In the intervention condition, patients with left-sided neglect receive intense training, including reading and visual spatial task with standardized and adapted visual cueing by the therapist. Improvements in reading and visual spatial tasks lead to a reduction of cues by the therapist. Accordingly, the patient has to apply self-cueing over time in order to solve the task.
For the control condition, all patients receive unspecific treatment without any standardized adapted cueing implemented by the therapist.
To enhance the effectivity of cueing in reading and visual spatial tasks, the investigators additionally conduct parietal transcranial direct current stimulation (tDCS) in those patients without tDCS exclusion criteria (see exclusion criteria below).
It is hypothesised that systematic and adaptive therapeutic cueing leads to a significant reduction of omissions of word and word parts in reading.
UPDATE: No Add-on tDCS was performed since it was not applicable for our severly impaired patients due to the strict exclusion criteria of tDCS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Left sided neglect
- •Capacity of at least 30 minutes
- •Ability to read in German language
- •Mobilization of 80%
排除标准
- •Previous known dementia
- •Normal pressure hydrocephalus
- •Exclusion Criteria for tDCS Add-on (not exclusion of the intervention):
- •Craniectomy
- •Other metal implants
研究组 & 干预措施
Intervention
- adaptive, therapeutic cueing during reading tasks
- adaptive, therapeutic cueing during visuo spatial tasks
干预措施: Cueing (Behavioral)
Control
- unspecific neglect treatment
结局指标
主要结局
Change in word and word-part omissions in standardized reading of text and word list
时间窗: Primary Outcome Measure is assessed two times in the first week (3 days in between), after week 4, after week 7, after week 8
the patient has to read a standardized text of 55 words and a word list of 13 words. Omissions of the complete word and/or of a word part are counted.
次要结局
- Change in activities of daily living using the Catherine Bergego Scale(Secondary Outcome Measure is assessed after week 1, after week 4, after week 7, after week 8)
- Change in standardized evaluation of the body posture(Secondary Outcome Measure is assessed two times in the first week (3 days in between), after week 4, after week 7, after week 8)
- Change in Apples Cancellation Task(Secondary Outcome Measure is assessed two times in the first week (3 days in between), after week 4, after week 7, after week 8)