NCT01890616已完成不适用
Constipation and Gut Transit in Duchenne Muscular Dystrophy Patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- GI transit times
研究概览
简要总结
In this research study the investigators want to screen Duchenne Muscular Dystrophy (DMD) patients for signs and symptoms of constipation in patients over 18.
The investigators hypothesized:
- DMD patients have a high prevalence of constipation than in the general population.
- Prevalence of constipation will increase with age and with worsening functional status.
详细描述
The following procedures will take place during the study.
Constipation Assessment:
- The patient will be asked to complete a questionnaire about any symptoms of constipation.
- A physician from the study team will perform an abdominal physical exam
- The patient will have routine x-rays that monitor for spine compression fractures. These films will also be used to assess stool content.
Clinical Information The following information will also be collected during the clinic visit ;
- Age at diagnosis and genetic mutation
- Age at loss of ambulation if applicable
- Medications
- Functional status
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Patients with a diagnosis of Duchenne Muscular Dystrophy (based on clinical presentation and verified by compatible muscle biopsy or known dystrophin gene mutation).
- •Age greater than or equal to 18 years old
排除标准
- 未提供
结局指标
主要结局
GI transit times
时间窗: up to 5 days
Gi transit times will be computed by an investigator.
次要结局
未报告次要终点
研究者
研究点 (1)
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