Regenerative Endodontic Treatment Using Sodium Hexametaphosphate (SHMP) For Necrotic Immature Permanent Anterior Teeth: In Vivo And In Vitro Study
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Normal responses to percussion, palpation, and normal pocket probing depths, and a positive response to pulp test
研究概览
简要总结
evaluate clinically and radiographically regenerative potential of sodium hexametaphosphate (SHMP) on stem cells from the apical papilla for 18-month randomized controlled trial
详细描述
7 to 11 years old will be selected with no sex predilection for the study from out patients of Pediatric and Community Dentistry Department, Minia University, according to the following eligibility criteria and evaluate clinically and radiographically regenerative potential of sodium hexametaphosphate (SHMP) on stem cells from the apical papilla for 18-month randomized controlled trial
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
盲法说明
-Included patients will be randomized into one of the study groups. Randomization will be performed using a computer-generated block randomization system (Microsoft office excel, 2007).
Concealment, A plan of management will be sealed in closed envelops, numbered according to the randomization tables.
Packing, sealing and numbering will all be performed by a neutral health care provider other than the investigator.
入排标准
- 年龄范围
- 7 Years 至 11 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Presence of necrotic anterior immature teeth. Parents accepting the treatment modality.History, clinical and radiographic examination reveals absence of pulp vitality Patient abruptly health
排除标准
- •Tooth mobility. Children who will not comply to recall program. Teeth with history of recurrent periapical pathosis. Hypersensitivity to any material used.
研究组 & 干预措施
Sodium Hexametaphosphate
dental material
干预措施: Sodium Hexametaphosphate (SHMP) Inorganic polyphosphates (poly[P]) are linear polymers of orthophosphate (Pi) residues linked by energy-rich phosphoranhydride bonds, Ithas multiple physiological funct (Biological)
结局指标
主要结局
Normal responses to percussion, palpation, and normal pocket probing depths, and a positive response to pulp test
时间窗: one year
pulp sensibility test
Absence of signs and symptoms of pain, absence of mobility or periapical lesion
时间窗: one year
PALS scale
次要结局
未报告次要终点
研究者
Ahmad Elheeny
Assistant professor of Pediatric and Community Dentistry, Faculty of Dentistry, Minia University
Minia University