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临床试验/NCT04213586
NCT04213586已完成不适用

Effects of Whey Protein and Collagen Supplementation on Muscle Mass and Function During Training in Young Adults

Universidade Norte do Paraná2 个研究点 分布在 1 个国家目标入组 22 人开始时间: 2019年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
22
试验地点
2
主要终点
Change in mean power

研究概览

简要总结

The present project aims to investigate the effects of high-quality protein (whey protein) vs. low-quality protein (collagen) on muscle mass and function (e.g., strength and power) during a 10-wk resistance training program in young adults. It will be tested the hypothesis that leucine-matched collagen should promote similar gains on muscle function and mass compared to whey protein supplementation.

详细描述

The purpose of this study will be to investigate the effects of whey protein vs. leucine-matched collagen supplementation on muscle mass and function after a 10-wk resistance training program. Initially, all participants will be submitted for a 2-wk familiarization period, and then randomized into two groups (N = 11 / group): whey protein group and leucine-matched collagen group. The following variables will be assessed from pre-to post-training: anthropometric, muscle thickness from vastus lateralis and biceps brachii muscles using ultrasound, training load, mean power and peak torque for unilateral arm flexion exercise using a isokinetic dynamometer, countermovement vertical jump, nutritional intake, and testosterone-to-cortisol ratio . Shapiro-Wilk and Levine tests will be used to test the normality and homogeneity of the measurements, respectively. Two-way ANOVA (group x time) tests for repeated measures will be performed to assess changes over time and between groups for all dependent variables. Violation of sphericity will adjust using Greenhouse- Geyser correction. The Bonferroni post-hoc test will detect specific differences between groups. When appropriate, the percentage of change (∆%) will be reported according to the following equation: ∆% = [(pre-average post average) / pre-average mean] × 100. Values will be express as mean ± standard deviation. O significance level α will be 0.05.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Men and women aged 18-35 years
  • To be eutrophic (not overweight or obese)

排除标准

  • To present a history of musculoskeletal disorders
  • Be attending a systematized weight training program for at least six months
  • To make use of medicines that could affect muscle function.
  • To have used ergogenic supplements and anabolic steroids for at least six months before study
  • To have restrictions for exercises practice considering Physical Activity Readiness Questionnaire (PAR-Q) responses.

结局指标

主要结局

Change in mean power

时间窗: Baseline and after 10 weeks

Mean power using a isokinetic dynamometer (BIODEX)

Change in peak torque

时间窗: Baseline and after 10 weeks

Peak torque using a isokinetic dynamometer (BIODEX)

Change in biceps brachii thickness

时间窗: Baseline and after 10 weeks

Measured by ultrasonography pre- and post-training

Change in vastus lateralis thickness

时间窗: Baseline and after 10 weeks

Measured by ultrasonography pre- and post-training

Change in vertical jump

时间窗: Baseline and after 10 weeks

Countermovement vertical jump performance will be assessed using the Smart Jump instrument

Change in muscle strength by training load

时间窗: Baseline, 5 and 10 weeks

Training load for leg press, knee extension, and arm flexion exercises

次要结局

  • Change in testosterone-to-cortisol ratio(Baseline and after 10 weeks)
  • Dietary intake(Baseline, 2, 5, 10 weeks)

研究者

发起方
Universidade Norte do Paraná
申办方类型
Other
责任方
Principal Investigator
主要研究者

Andreo Fernando Aguiar

Principal Investigator

Universidade Norte do Paraná

研究点 (2)

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Effects of Whey Protein and Collagen Supplementation | 临床试验