Study on the Response to Tetanus Vaccination of People Living With HIV
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 210
- 试验地点
- 2
- 主要终点
- the vaccine response to tetanus vaccination
研究概览
简要总结
The response to primary tetanus immunization of HIV-infected children is lower than that of uninfected children.
Response to tetanus toxoid (TT) booster doses in adults living with HIV who have received primary vaccination prior to infection is not known.
Currently, it is recommended to have a TT booster for people living with HIV (PLHIV) every 10 years. In general population, this recall is made only at 25, 45 and 65 years, then every 10 years.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Person aged ≥ 18 years
- •Person infected with HIV followed in the infectious diseases department of CH Niort
- •Born in France
- •Affiliate or beneficiary of a social security scheme
- •Being able to give free and informed consent to participation in research
排除标准
- •Persons with a contraindication to tetanus vaccination
- •Persons under guardianship or curatorship or without civil law
结局指标
主要结局
the vaccine response to tetanus vaccination
时间窗: Month 6
An anti-tetanus IgG level\> 0.1 is considered long-term protective. An anti-tetanus IgG level between 0.01 and 0.1 is considered protective in the short term. The measurement of the vaccine response will be correlated with the age of the last VAT recall (\<10 years, between 10 and 20 years,\> 20 years and unknown)
次要结局
未报告次要终点