NCT02632578已完成不适用
A Comparison of Immune Responses to the Licensed Trivalent Inactivated Influenza Vaccine in HIV-positive and HIV-negative Subjects
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 57
- 主要终点
- Anti-influenza antibody responses in plasma with Fc-mediated functions
研究概览
简要总结
The aims of this study are:
- to investigate if HIV infection alters the antibody responses to influenza and
- to assess the ability of licensed influenza vaccine to induce functional non-neutralising antibodies in HIV-infected and HIV-uninfected subjects.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •HIV-1 positive by licensed diagnostic test (for HIV-positive group only)
- •Planning to receive the seasonal influenza vaccine outside the study
- •Provision of written informed consent
排除标准
- •Previous allergy to influenza vaccination
- •Pregnancy or planning to become pregnant
- •Unwilling or unable to provide blood samples
结局指标
主要结局
Anti-influenza antibody responses in plasma with Fc-mediated functions
时间窗: Four weeks after influenza vaccination
次要结局
未报告次要终点
研究者
Prof Stephen Kent
Professor
University of Melbourne
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