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临床试验/NCT05342324
NCT05342324已完成不适用

Optical Coherence Tomography Angiography in Choroidal Osteoma: a Quantitative Evaluation of Choriocapillary Vessel Density

Federico II University1 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2015年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
28
试验地点
1
主要终点
Study of vessel density of the choriocapillary in patients affected by choroidal osteoma .

研究概览

简要总结

This study evaluates the vessel density of choriocapillary vascular network in eyes affected by choroidal osteoma and in eyes complicated by choroidal neovascularization, using optical coherence tomography angiography.

详细描述

The choroidal osteoma is a rare benign tumor of choroid, it is bilateral in 10%-25% of cases, affecting usually young women. Previous studies evaluated the morphologic characteristics of tumor-related vasculatures, described as a seafun vascular networks, but none focused on study of vessel density of coriocapillary.

The aim of this study is to investigate the potential role of the optical coherence tomography angiography (OCTA) in evaluating the choriocapillary vessel density in order to individuate the changes of this vascular network that may influence the onset of choroidal neovasculariztion.

Therefore, OCTA could be useful in the clinical management of the choroidal osteoma

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
50 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age older than 50 years
  • diagnosis of choroidal osteoma
  • absence of history of vitreoretinal and vascular retinal diseases

排除标准

  • age younger than 50 years
  • no diagnosis of choroidal osteoma
  • presence of history of vitreoretinal and vascular retinal diseases

结局指标

主要结局

Study of vessel density of the choriocapillary in patients affected by choroidal osteoma .

时间窗: 7 years

To evaluate the role of optical coherence tomography angiography in evaluating the features of the choriocapillary, using optical coherence tomography angiography (OCTA) in patients with choroidal osteoma and in patients with choroidal osteoma complicated by choroidal neovascularization. The parameter analyzed by OCTA was the vessel density of choriocapillary (percent)

次要结局

未报告次要终点

研究者

发起方
Federico II University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Gilda Cennamo

Principal Investigator

Federico II University

研究点 (1)

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