NCT07663149已完成不适用
Effectiveness of Continuous Phenylephrine in Preventing Shivering After Spinal Anesthesia in Cesarean Section
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 108
- 试验地点
- 1
研究概览
简要总结
This study aims to evaluate the effectiveness of continuous phenylephrine infusion at 50 mcg/min in preventing shivering after spinal anesthesia in cesarean section.
This study was an open-label randomized clinical trial involving patients undergoing cesarean section under spinal anesthesia. Subjects were allocated into two groups: without phenylephrine and continuous phenylephrine infusion at 50 mcg/min. The primary outcome was the incidence of shivering during observation, assessed using the Crossley and Mahajan scale. Secondary outcomes included hypotension, ephedrine requirement, hemodynamic adverse events, and nausea vomiting.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Females aged 18-50 years.
- •Patients undergoing a Cesarean section procedure under spinal anesthesia.
- •Patients who are not in labor (non-labor).
- •Patients willing to participate in this study.
排除标准
- •Patients with contraindications to phenylephrine.
- •Patients with allergies to the study medications.
- •Presence of fever (temperature >37.5°C) or hypothermia (temperature <35°C).
- •American Society of Anesthesiologists (ASA) score of III or higher.
- •Patients with a history of untreated thyroid disease.
- •Patients with a history of autonomic nervous system neuropathy.
- •Hypertension in pregnancy (or gestational hypertension).
- •Body Mass Index (BMI) greater than 35 kg/m².
研究者
Alfan Mahdi Nugroho
dr. Alfan Mahdi Nugroho Sp.An-TI, Subsp.AO(K), Subsp.AR(K)
Indonesia University
研究点 (1)
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