Vaginal Wound Infiltration Analgesia for Postoperative Pain After Laparoscopic Hysterectomy: a Randomized Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 81
- 主要终点
- Postoperative pain scores
研究概览
简要总结
In cases of laparoscopic hysterectomy , women were randomized to two groups: ropivacaine ( vaginal wound infiltration analgesia) vs. control group. Results regarding postoperative pain and need of oxycodone.
详细描述
Women assigned to laparoscopic hysterectomy were randomly divided into two groups as regard surgery: a ropivacaine group (RG) (n=41) and a control group (CG) (n=40). General anesthesia and use of local anesthetics were standardized. Visual analog scale (VAS) scores for pain and side effects (nausea/vomiting) and the amount of postoperative analgesic used were recorded for 24 hours.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 接受健康志愿者
- 否
入选标准
- •The criteria for inclusion were scheduled laparoscopic hysterectomy
排除标准
- •The exclusion Criteria were contraindications to any of the forms of medication used in the study (oxycodone, ketoprofen, paracetamol), language difficulties ( inability to understand and speak Finnish or Swedish)
结局指标
主要结局
Postoperative pain scores
时间窗: Change in 24 hours after surgery
Visual Analog Score (VAS) for pain. Physicians Global Assessment to measure quality of pain. 10-point VAS score for pain (0-10), 0 indicating no pain and 10 indicating unbearable pain at 1,3,6,12 and 24 h (hour) after surgery (Units on a Scale; 0-10).
次要结局
- Complication(Up to one week)
- Nausea(Change in 24 hours after surgery.)
- Length of hospitalisation(Up to one week)
- The use of analgesics for postoperative pain(Change in 24 hours after surgery)
- Vomiting(Change in 24 hours after surgery.)
研究者
Päivi Päkarinen
MD PhD
Helsinki University Central Hospital