NCT00759005已完成不适用
Effect of Stress on Heroin-Related Memory Retrieval
National Institute on Drug Dependence, China1 个研究点 分布在 1 个国家开始时间: 2007年3月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 试验地点
- 1
- 主要终点
- Glucocorticoids enhanced heroin-related memory retrieval in abstained heroin addicts
研究概览
简要总结
The purpose of this study is to determine whether cortisol and propranolol are effective in the modulation of stress induced heroin-related retrieval enhancement.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Participants had to have met DSM-IV criteria for heroin dependence prior to abstinence.
排除标准
- •current use of any medications; current DSM-IV diagnosis of any affective, anxiety, or psychotic disorder; current dependence on any substance besides heroin and nicotine (based on DSM-IV criteria); or risk factors for untoward side effects from propranolol and cortisol (i.e., irregular heartbeats, history of cardiogenic shock, history of severe heart failure, asthma, fungal Infections, hyperlipidemia, history of hypertension, or abnormal ECG or other laboratory findings).
研究组 & 干预措施
A, 4
Experimental
干预措施: propranolol and cortisol (Drug)
结局指标
主要结局
Glucocorticoids enhanced heroin-related memory retrieval in abstained heroin addicts
次要结局
未报告次要终点
研究者
研究点 (1)
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