The effect of hyperbaric oxygen therapy on breast cancer patients with late radiation toxicity - UMBRELLA HONEY

niversity Medical Center Utrecht0 个研究点目标入组 120 人开始时间: 2019年10月14日最近更新: 2023年10月16日

试验速览

暂无简介。

•-Self reported pain grade 3-4 (on a scale of 1-4) as assessed by the late radiation toxicity questionnaire
•-Participation >12 months in the UMBRELLA cohort;
•-Previous treatment with radiotherapy for breast cancer;
•-Finished surgery and (neo)adjuvant systemic therapy except adjuvant endocrine therapy, for breast cancer.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 80
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 40

•-Poor responder (i.e. return of =2 UMBRELLA questionnaires);
•-Previous HBOT;
•-Contra-indications for HBOT (e.g. (severe) COPD/asthma, pacemaker, morbid obesity, epilepsy in medical history, severe heart failure);
•-Current metastatic disease or recurrent breast cancer.
•Additional exclusion criteria based on screening visit
•-Inability to follow schedule of all consecutive HBO treatments (e.g. due to scheduled holidays > 2 days);
•-Not meeting criteria for HBOT (e.g. due to complaints similar to late radiation toxicity, not caused by radiotherapy).

发起方