Correlation of Serum CA19-9 Levels With Levels in Saliva and Urine of Patients With Ductal Adenocarcinoma of the Pancreas
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- correlation of CA19-9 levels in urine and saliva with those in the serum
研究概览
简要总结
Ductal adenocarcinoma of the pancreas is the fifth leading cause of cancer related deaths in the European Union. Tumor markers CA19-9 and carcinoembryonic antigen are important components in decision making and follow-up of patients diagnosed with this disease.
These tumor markers were found to be elevated not only in the serum but also in other body fluids in patients with malignant lesions of the parotid gland and the urinary tract. The authors have described in a previews small preliminary study a positive and a strong linear correlation between the levels of CA19-9 in urine and saliva with those presented in the serum of patients with ductal adenocarcinoma of the pancreas. The current study seeks to enlarge the study population to confirm the previous results and standardize the measured levels of CA19-9 in these body fluids.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Proven diagnosis of ductal adenocarcinoma of the pancreas
- •elevated levels of CA19-9
- •possible elevated levels of CEA
排除标准
- •Previous diagnosis of malignancy
研究组 & 干预措施
Patients
Patients with a proven diagnosis of ductal adenocarcinoma of the pancreas with elevated levels of CA19-9 and possibly elevated CEA levels.
intervention: samples of blood, saliva and urine
干预措施: samples of blood, saliva and urine (Other)
Control
Patients or healthy volunteers with out a known evidence of malignancy with presumably normal levels of CA19-9 and CEA.
intervention: samples of blood, saliva and urine
干预措施: samples of blood, saliva and urine (Other)
结局指标
主要结局
correlation of CA19-9 levels in urine and saliva with those in the serum
时间窗: 1 year
次要结局
- Number of participants needed to standardize the measurements in urine and saliva according to those measured in the serum.(1 year)
