ISRCTN15078551进行中（未招募）Unknown
Comparative efficacy and safety of upadacitinib versus oral prednisolone for the induction and maintenance of remission in moderate to severe ulcerative colitis: a prospective, multicenter, open-label, randomised controlled trial (PREDUPA Trial)
适应症
试验速览
- 阶段
- Unknown
- 状态
- 进行中（未招募）
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1.Males + Females with moderate-to-severe UC
- •2.Age 18 – 60 years
- •3.All durations of disease
- •4.All extents of disease (proctitis / left-sided colitis / pancolitis)
- •5.Previously failed to respond to conventional therapies and/or anti-TNF therapy
- •6.Biologic-naïve
- •7.On a stable dose of 5-ASA or immunomodulator four weeks prior to the start of the study
排除标准
- •1.Pregnant / lactating
- •2.Crohn’s colitis
- •3.Latent or active TB
- •4.Active infection
- •5.Current or past malignancy
- •6.Active or past thromboembolic disease
研究者
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