Mitochondrial Capacity in Young and Elderly Males

WO, TIF0 个研究点目标入组 40 人开始时间: 待定最近更新: 2024年6月11日

适应症

试验速览

暂无简介。

•Male, 19-25 years
•BMI 18.5-27 kg/m2
•Normal activity levels: 1-2 hour per week engaged in a structured exercise session
•Male, 65-71 years
•BMI 18.5-27 kg/m2
•Normal activity levels: 1-2 hour per week engaged in a structured exercise session
•Short physical performance battery score >6

•(known symptoms of) Metabolic diseases, e.g. type I or II diabetes,
•Health concerns regarding respiratory and pulmonary diseases, e.g. COPD, (exercise induced) asthma and cardiovascular disease.
•Impaired physical performance (defined as short physical performance battery score < 6) (Only for elderly group)
•Contraindications for electrical stimulation, e.g. cardiac pacemaker
•Contraindications for muscle biopsy, e.g. usage of anticoagulants (low dose aspirin allowed)
•Regular smoker (defined as smoking >5 cigarettes per week)
•Vastus lateralis skinfold >30mm
•Haemoglobin concentrations below 8.0 mmol/L
•Usage of recreational drugs, e.g. marihuana, amphetamines and cocaine during the study (starting after first screening day)
•Recent usage (within four months) of supplements with suggestive training effects, e.g. creatine phosphate, EPO or anabolic steroids.
•Current or recent (<2 weeks) participation in other clinical trials

发起方

WO, TIF