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临床试验/NCT04211779
NCT04211779Unknown不适用

The Effect of Anodal Transcranial Direct Current Stimulation Combined With Aerobic Exercise on Performance in Healthy Individuals

Marmara University1 个研究点 分布在 1 个国家目标入组 21 人开始时间: 2020年3月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
21
试验地点
1
主要终点
Effect of tDCS combined with aerobic exercise on exercise performance in healthy individuals.

研究概览

简要总结

The purpose of this study is to assess the effects on the exercise performance of anodal transcranial direct current stimulation combined with aerobic exercise in healthy individuals.

详细描述

Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation method that has become increasingly popular in recent years. tDCS shows promising improvements for the motor performance of healthy individuals as well as pathological conditions. Moreover, it is frequently preferred because of its safety advantage, high tolerability as well as being cheap, portable and easily applicable.

Studies have shown that tDCS can modulate the excitability of both cortical and subcortical brain regions. In recent years, there have been scientific studies investigating the effects of tDCS on improving physical performance in healthy individuals, but these studies are limited in number, their results are conflicted and as far as the investigators know there is no study that combines tDCS with exercise.

Moreover, although the mechanisms of tDCS on physical performance are largely unknown, some tDCS devices are open to public usage and a large number of professional athletes have reported using tDCS during their training programs. Therefore, studies are needed to demonstrate the effects of tDCS which combined with exercise on performance.

The aim of this study was to investigate the effects of anodal transcranial direct current stimulation combined with aerobic exercise on physical performance in healthy individuals.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
20 Years 至 25 Years(Adult)
性别
Male
接受健康志愿者
是

入选标准

  • •Healthy subject
  • •No use of any ergogenic substance in one year
  • •No history of active exercise training in last 6 months

排除标准

  • •Pacemaker
  • •Intracerebral metallic implant
  • •Using dietary supplementation or medication potentially affecting the CNS
  • •Musculoskeletal injury within the past 6 weeks
  • •Lower extremity pain above 3 or more according to numeric pain scale
  • •History of epilepsy or convulsive crisis

研究组 & 干预措施

Real tDCS and Exercise

Experimental

tDCS (tDCS - TCT Research Limited, Hong Kong) / Exercise Group in which will receive the active intervention of aerobic exercise training and active tDCS intervention at the same time.

干预措施: Real tDCS (Device)

Real tDCS and Exercise

Experimental

tDCS (tDCS - TCT Research Limited, Hong Kong) / Exercise Group in which will receive the active intervention of aerobic exercise training and active tDCS intervention at the same time.

干预措施: Exercise (Other)

Sham tDCS and Exercise

Sham Comparator

Sham tDCS (tDCS - TCT Research Limited, Hong Kong) / Exercise Group in which will receive the active intervention of aerobic exercise training and sham tDCS intervention at the same time.

干预措施: Sham tDCS (Device)

Sham tDCS and Exercise

Sham Comparator

Sham tDCS (tDCS - TCT Research Limited, Hong Kong) / Exercise Group in which will receive the active intervention of aerobic exercise training and sham tDCS intervention at the same time.

干预措施: Exercise (Other)

Exercise

Other

Exercise group in which will receive the active intervention of aerobic exercise training no tDCS intervention.

干预措施: Exercise (Other)

结局指标

主要结局

Effect of tDCS combined with aerobic exercise on exercise performance in healthy individuals.

时间窗: 2 months

The performance will be evaluated by measuring the maximal consumption of oxygen (VO2max). VO2max will be assessed continuously during the time to exhaustion trial using a gas analyzer

Effect of tDCS combined with aerobic exercise on ratings of perceived exertion (RPE) in healthy individuals.

时间窗: 2 months

RPE will be assessed continuously (every 3 minutes) during the time to exhaustion trial using the Borg rating of perceived exertion scale (RPE scale). The Borg RPE scale is a quantitative measure of perceived exertion during physical activity. The scale starts with "no feeling of exertion," which rates a 6, and ends with "very, very hard," which rates a 20. Moderate activities register 11 to 14 on the Borg scale ("fairly light" to "somewhat hard"), while vigorous activities usually rate a 15 or higher ("hard" to "very, very hard").

次要结局

  • Effect of tDCS combined with aerobic exercise on isokinetic muscle strength in healthy individuals.(2 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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