NCT06107166已完成不适用
Testosterone and Vascular Function in Reproductive-Aged Females With Chronic Kidney Disease
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 61
- 试验地点
- 1
- 主要终点
- Aortic augmentation index
研究概览
简要总结
Cardiovascular disease (CVD) is the leading cause of death among women and women with chronic kidney disease are at an even greater risk of CVD. The aim of this observational study is to examine the relationship between total testosterone levels and measures of vascular function (pulse wave velocity, aortic augmentation index, flow mediated dilation and velocity time integral) in reproductive-aged women living with chronic kidney disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 51 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •female sex
- •a diagnosis of chronic kidney disease or end stage kidney disease
- •age 18-51
排除标准
- •Pregnancy, breastfeeding, current use of menopausal hormone therapy or gender affirming hormone therapy, or factors that would affect ovarian function, such as polycystic ovarian syndrome, premature ovarian insufficiency, ovarian malignancy, gonadotoxic chemotherapy, surgical oophorectomy, or previous radiation to the pelvis.
结局指标
主要结局
Aortic augmentation index
时间窗: Measured at baseline
Flow mediated dilation
时间窗: Measured at baseline
Pulse wave velocity
时间窗: Measured at baseline
Velocity time integral
时间窗: Measured at baseline
次要结局
未报告次要终点
研究者
Sandra Dumanski
Assistant Professor
University of Calgary
研究点 (1)
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