Systemic Inflammatory Indices as a Non-invasive Grading Modality for Endometriosis: A Comparative Study Versus Exploratory Laparoscopy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 88
- 试验地点
- 1
- 主要终点
- Indices' ability to predict EM stage
研究概览
简要总结
Endometriosis (EMs) is one of the commonest chronic inflammatory disorder affecting women and is characterized by the presence and growth of endometrial-like glandular epithelial and stromal cells outside the uterus leading to multiple clinical symptoms affecting patients quality of life and fertility with high recurrence rate . The systemic immune inflammatory index (SII) and systemic inflammatory response index (SIRI) are documented as prognostic serum biomarker in many kinds of cancer and for the need and outcomes of adjuvant therapies for various cancers .
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 25 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women with clinical manifestations suggestive of having EM;
- •Women who was professionally diagnosed;
- •Women who was diagnosed by radiologic workup;
- •Women were free of exclusion criteria.
排除标准
- •Women with EM and were maintained on treatment or underwent operative interference during the last three months;
- •Patients had autoimmune diseases, maintained on immunosuppressive therapy for any indication;
- •Women with cancer elsewhere in the body or receiving adjuvant therapies for cancer;
- •Patients receiving therapies for viral disorders especially COVID;
- •Patients refusing to undergo the exploratory laparoscopy.
结局指标
主要结局
Indices' ability to predict EM stage
时间窗: 8 months
Number of patients was diagnosed with EM and got staged right through a calculated indices to the patients who went for exploratory laparoscopy which improve the chances of calculated indices facing the laparoscopy.
次要结局
未报告次要终点
研究者
Ahmed Sabra
Lecturer of Obstetrics & Gynecology Department, Faculty of Medicine.
Benha University