Development of Machine Learning Models for the Prediction of Complications After Colonic, Colorectal and Small Intestine Anastomosis in Psychiatric and Non-psychiatric Patient Collectives (P-Study)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 10,000
- 试验地点
- 1
- 主要终点
- Complication after surgery/ Comprehensive Complication Index/ Clavian Dindo Score
研究概览
简要总结
Our study aims to lay the basis for a predictive modeling service for postoperative complications and prolonged hospital stay in patients suffering from psychiatric diseases undergoing colorectal surgery.
Furthermore, we aim to investigate the impact of preoperative Risk factors, psychiatric and psychosomatic diseases on the outcomes of colorectal surgery and the complications after colorectal surgeries like anastomosis insufficiency via predictive modeling techniques
The service mentioned above will be publicly available as a web-based application
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Colocolic, colorectal and small intestine anastomosis
- •Neoplasia,
- •Diverticulitis
- •Mesenteric ischemia
- •Iatrogenic or traumatic perforation
- •Inflammatory bowel disease
排除标准
- •Patients <18 years
- •Patients suffering from recurrent colorectal cancer bearing
- •Peritoneal carcinomatosis or unresectable metastatic disease at the time of bowel resection and anastomosis will be excluded.
- •Patients who cannot be followed up on for more than six weeks after surgery
结局指标
主要结局
Complication after surgery/ Comprehensive Complication Index/ Clavian Dindo Score
时间窗: From index surgery up to six weeks postoperatively
Impact of psychatric and psychosomatic disorders are having higher complication rates
Intraoperative influid manangment
时间窗: Time Frame: From index surgery up to six weeks postoperatively
Impact of Intraoperative influid on the development of anastomotic insuffiency
Length of Hospital Stay (in Days)
时间窗: From surgery up to 12 weeks postoperatively
Impact of psychatric and psychosomatic disorders are having longer hospitalization
Development of a preoperative score for morbidity/mortality in colorectal surgery
时间窗: From index surgery up to six weeks postoperatively
Check the risk for morbidity/mortality in colorectal surgery
Anastomotic insufficiency/leakage
时间窗: From index surgery up to six weeks postoperatively
Predictive model with an app for the development of anastomosis insufficiency based on the risk factors.
次要结局
未报告次要终点
研究者
Dr. Med Anas Taha
Research Fellow
University of Basel