Assessment of COVID-19 Associated Coagulopathy and Hypercoagulable State in Upper Egypt
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 106
- 试验地点
- 1
- 主要终点
- Thrombophilia screen
研究概览
简要总结
Coagulopathy is one of the most significant prognostic factors in patients with COVID-19 and is associated with increased mortality and admission to critical care. Most commonly observed coagulopathy in patients hospitalized with COVID-19 (COVID-19-associated coagulopathy) is characterized by increased D-dimer and fibrinogen levels. 71% of patients who did not survive hospitalization reported to have developed disseminated intravascular coagulation (DIC) compared to 0.6% of survivors.
详细描述
studying the detailed coagulation screen and second line coagulation parameters including both thrombophilia screen and other acute phase coagulation factors.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with COVID 19 positive by RT- PCR
排除标准
- •no exclusions
结局指标
主要结局
Thrombophilia screen
时间窗: 1 month
Full thrombophilia screen
VWF, FVIII
时间窗: 1 month
VWFAg, FVIII
Coagulation screen
时间窗: 1 month
Full coagulation screen
次要结局
未报告次要终点
研究者
Azza Abdelaal
lecturer of clinical pathology
Assiut University