Correlation of Serum and Semen Vitamin D Level With Semen Parameters in Males
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- correlation of serum and semen vitamin D level with semen parameters in males
研究概览
简要总结
vitamin D may have multiple functions, one of them is modulating reproductive processes and the reproductive role of vitamin D is highlighted by expression of the vitamin D receptors in testis, male reproductive tract and sperms
详细描述
Semen analysis is the corner stone of infertility evaluation as it provides information on the functional status of the seminiferous tubules, epididymis and accessory sex glands. The methods on how the semen should be evaluated are provided by the World Health Organization Vitamin D is synthesized mainly in the skin, where ultraviolet ray B radiation converts 7-dehydrocholesterol to Vitamin D3. Then, Vitamin D3 undergoes two hydroxylation processes first in the liver and second in the kidney Serum 25(OH)D is the major circulating metabolite of vitamin D and reflects vitamin D inputs from cutaneous synthesis and dietary intake. The serum 25(OH)D level is the standard clinical measure of vitamin D status Vitamin D deficiency has been linked to various health disorders including boneheallth, cardiovascular, infectious, oncologic, musculoskeletal, neuropsychologic and reproductive disorders, as well as to overall mortality
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 50 Years(Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Varicocele.
- •Genital tract infections.
- •Primary and secondary hypogonadism
- •Hormonal therapy.
- •Calcium and vitamin D supplement.
- •Hepatic or renal failure
- •Diseases or drugs affecting vitamin D absorption -
结局指标
主要结局
correlation of serum and semen vitamin D level with semen parameters in males
时间窗: A year
evaluation the level of vitamin D in serum and semen by using ELISA method and correlate it with semen parameters
次要结局
未报告次要终点
研究者
Mary Yonan
Principal investigator
Assiut University
