NL-OMON35579尚未招募不适用
Muscle relaxation time as outcome measure in patients with non-dystrophic and dystrophic myotonic syndromes; voluntary handgrip- versus peripheral nerve stimulation myometry - Muscle-RT measurements in DMs and NDMs
niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 0 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Patients with a genetically confirmed mutation in the gene encoding for the skeletal muscle sodium channel (SCN4A) or chloride channel (CLCN1) or a genetically determined mutation in the DMPK-gene, with clinical presence of hand (action) myotonia and between 18 and 65 years of age. Groups will be age and sex matched.
排除标准
- •Comorbidity in form of a neurological or metabolic disorder that can interfere with normal muscle function. Usage of medication that can influence myotonia or muscle force (such as sodium channel blockers as widespreas used for cardiological and neurological diseases, that might also influence skeletal muscle channels). Cardial or Nephrological comoborbidity that do not allow a potassium low diet. Pregnant women. Unwillingness or unable to sign informed consent forms or to place the hand or lower arm in de myometry test set-up.
研究者
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