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临床试验/NCT06791382
NCT06791382招募中不适用

Predicting Hospital-Acquired Infections Using Electronic Health Records: An AI-Assisted Approach

The Eye Hospital of Wenzhou Medical University2 个研究点 分布在 1 个国家目标入组 1,000,000 人开始时间: 2023年2月1日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
1,000,000
试验地点
2
主要终点
Area Under the Curve (AUC)

研究概览

简要总结

This is a multi-center, clinical study designed to evaluate the application and effectiveness of an AI-assisted predictive model for identifying and diagnosing infection, leveraging multimodal health data.

详细描述

Hospital-acquired infections (HAIs) are a significant cause of morbidity and mortality in healthcare settings. Early identification and prevention of HAIs are crucial for improving patient outcomes, reducing healthcare costs, and preventing the spread of infections. In clinical practice, healthcare providers often need to integrate a wide range of patient data, including medical history, laboratory test results, medication usage, surgical procedures, and clinical observations, to assess infection risks and prevent HAIs. As infection control and precision medicine become increasingly important, the challenge remains to predict and prevent infections, especially in patients with subtle or asymptomatic risk factors. Recent advancements in artificial intelligence and data analysis techniques have shown great promise in improving the accuracy and efficiency of infection prediction and prevention. This study aims to develop an AI-assisted decision-making system by integrating multimodal data from electronic health records, lab results, clinical observations, and patient demographics. The objective is to enhance the early identification of patients at risk for HAIs, streamline clinical workflows, and optimize infection control measures. Ultimately, this system seeks to reduce the incidence of hospital-acquired infections, improve patient safety, and enhance overall healthcare quality.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Other

入排标准

年龄范围
0 Years 至 90 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with complete and accessible EHR data, including medical history, laboratory test results, treatment regimens, clinical observations, and infection history.
  • Patients who have been admitted to the participating hospital or healthcare facility during the study period.
  • All participants must provide informed consent to use their health data for research purposes.

排除标准

  • Patients with incomplete or missing critical EHR data, such as lab results, medical history, or treatment details, which are necessary for infection prediction.
  • Patients who have severe cognitive disorders, dementia, or conditions that prevent them from providing informed consent or participating in the study.
  • Patients who have not been admitted to the hospital during the study period or who are receiving outpatient care only.
  • Patients with terminal conditions where infection prediction may not be applicable to the clinical goals of the study.

结局指标

主要结局

Area Under the Curve (AUC)

时间窗: 1 year

AUC of the ROC curve, used to quantify diagnostic accuracy. No unit (a ratio or percentage, typically expressed as a number between 0 and 1).

F1 Score

时间窗: 1 year

The F1 score is the harmonic mean of precision and sensitivity (recall). It is a good measure of the model's ability to identify both true positives and minimize false positives, especially in cases where the classes are imbalanced (e.g., when the number of healthy cases is much higher than disease cases). The F1 score ranges from 0 to 1, with 1 indicating perfect precision and recall.

次要结局

  • Sensitivity (True Positive Rate)(1 year)
  • Specificity (True Negative Rate)(1 year)

研究者

发起方
The Eye Hospital of Wenzhou Medical University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Kang Zhang

Chief Scientist

Wenzhou Medical University

研究点 (2)

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