Effect of Dietary Composition on the Gut Microbiota / Endocannabinoidome Axis in Response to Maximal Aerobic Exercise
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 2
- 主要终点
- Endocannabinoid level post physical activity
研究概览
简要总结
Both the endocannabinoid system and the microbiome are highly conditioned by nutrition and physical activity, and have an interdependent, bidirectional relationship. We suggest studying the interleaving between the endocannabinoidome-microbiome axis and host metabolism under the combined effect of a diet and physical activity. More specificly, we will study the link between the impact of the diet on the intestinal microbiome and the endocannabinoid reaction after intense exercise.
详细描述
Aims of the study are to compare the impacts of two short 7-day contrasted nutritional interventions (the Mediterranean diet (MED) and the Canadian diet (CAN)) on blood metabolites (endocannabinoids) after a maximal aerobic test. A 3 weeks washout between the two diets is planned. Gut microbiome at each test will also be evaluated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 30 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •20-30 years old
- •jogging >1h/week and >3h/week of physical activity
- •bmi 18.5-25
排除标准
- •postmenopausal, pregnancy or lactation
- •pathology or medication
- •more than 7 alcohol consumption/week
- •food allergy, food intolerance or food aversion
- •important weight change in the last 6 months
- •antibiotics in the last 3 months
- •night worker
- •pathologies
结局指标
主要结局
Endocannabinoid level post physical activity
时间窗: 6 months
次要结局
未报告次要终点