Clinical Value of the Relationship Between Oral Lichen Planus and Autoimmune Thyroid Diseases
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Oral lichen planus (OLP) lesions record
研究概览
简要总结
On the basis of previous studies, a validation cohort will be established to explore the relationship between oral lichen planus and autoimmune thyroid diseases, and a disease efficacy prediction strategy can be formed.
详细描述
For oral lichen planus patients, the prevalence of Hashimoto's thyroiditis will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined.
Besides, for patients with Hashimoto's thyroiditis, the prevalence of oral lichen planus will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •OLP patients without systemic disease
排除标准
- •OLP patients with severe periodontal disease
结局指标
主要结局
Oral lichen planus (OLP) lesions record
时间窗: 1 year
Record changes of lesions based on the symptoms and signs of the oral lichen planus patient.
Level of thyroid function and antibody
时间窗: 1 year
The levels of thyroid hormone and thyroid autoantibodies in serum of OLP patients were detected.
次要结局
未报告次要终点
研究者
Qianming Chen
professor
The Dental Hospital of Zhejiang University School of Medicine