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临床试验/NCT03431376
NCT03431376已完成不适用

Potato Consumption Is Prospectively Associated With Risk of Hypertension: An 11.3-year Longitudinal Cohort Study

Zhejiang University0 个研究点目标入组 11,763 人开始时间: 2018年2月13日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
11,763
主要终点
Hypertension

研究概览

简要总结

Government has popularized potatoes as a major staple food in China. Potato, a potassium-rich food with high glycemic responses after consumption, exhibits unclear effects on hypertension. In this study, the investigators aimed to examine the association between potato consumption and hypertension risk among Chinese people.

详细描述

Potato is considered as a superior crop due to its significant nutritive value and great production yield. China is the largest potato producer with a quarter of world production, followed by India, Russia, and USA. The potato production as well as consumption has enhanced in developing countries while continuously declined in developed countries during the last decade. The investigators therefore explored the prospective associations of consumption of total potatoes, sweet potatoes, stir-fried potatoes, and non stir-fried potatoes with the risk of hypertension in general people of the China Health and Nutrition Survey (CHNS) cohort study from 1989 to 2011. A total of 11,763 participants (≥20 years old) who were free of hypertension at baseline were enrolled from CHNS Cohort study. Cox proportional hazards regression models were used to estimate the associations after adjusting for potential confounders. This study provides new evidence on the association of various potato consumption with the incidence of hypertension in China. As urbanization accelerates across the whole domain of China, the tendency of transition to Western-style diets and lifestyles appears continuously and steeply growing. More and more potatoes will be consumed as processed potato products including potatoes chips and French fries, which may be a potential risk factor of hypertension occurrence.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 93 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults aged 20-93 with complete data on diet and follow-up time
  • Adults with no chronic disease history

排除标准

  • Adults aged < 20 years
  • Identified to be pregnant
  • Previously diagnosed with hypertension, cancers, infarction, apoplexy, and diabetes

结局指标

主要结局

Hypertension

时间窗: From entry into the study (baseline: 1989-2009) until 2011

Incidence of hypertension, on basis of self-reported physician diagnosis, systolic blood pressure ≥ 140 mm Hg, diastolic blood pressure ≥ 90 mm Hg, or previous diagnose of hypertension by a physician or current use of anti-hypertensive drugs

次要结局

  • Potato consumption(From entry into the study (baseline: 1989-2009) until 2011)

研究者

发起方
Zhejiang University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Yu Zhang

Professor

Zhejiang University

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