Comparative Efficacy of Diode Laser Photobiomodulation Combined With CPP-ACPF Varnish Versus CPP-ACPF Varnish Alone in the Management of Dentin Hypersensitivity: A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 70
- 主要终点
- Reduction in dentin hypersensitivity in response to evaporative (air-blast) stimulus
研究概览
简要总结
This study aims to compare the effectiveness of diode laser photobiomodulation combined with CPP-ACPF varnish versus CPP-ACPF varnish alone in reducing dentin hypersensitivity. Participants diagnosed with dentin hypersensitivity will receive either the combined treatment or varnish application alone. Pain levels will be evaluated using a standardized visual analog scale before and after treatment sessions. The results of this study may help determine whether adding diode laser therapy enhances the effectiveness of conventional varnish treatment in managing dentin hypersensitivity.
详细描述
This study is a clinical trial designed to evaluate the effectiveness of two treatments for dentin hypersensitivity, which is the pain or discomfort felt when teeth are exposed to hot, cold, sweet, or touch.
Participants who meet the study criteria will be randomly assigned to one of two groups:
Group A: Treatment with a diode laser combined with CPP-ACPF varnish applied to the sensitive teeth.
Group B: Treatment with CPP-ACPF varnish alone.
Study Procedures:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcome assessor and analyst will be blinded to the intervention group assigned to the patients.
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult participants aged from 20 to 50 years of age.
- •Participants with good oral hygiene.
- •Presence of at least one tooth with dentin hypersensitivity confirmed by the air blast and/or tactile stimuli (scoring ≥3 on the VAS).
- •Participants willing to cooperate and attend recall appointments
- •Teeth with Non-Carious Cervical Lesions.
- •Patients with dentin hypersensitivity due to GERD and Parafunctional habits e.g., bruxism.
- •Patients with dentin hypersensitivity associated with gingival recession.
排除标准
- •Participants with poor oral hygiene.
- •History of professional or at-home desensitizing treatment within the previous 3 months.
- •Pregnant or lactating females.
- •Concurrent participation in other research studies.
- •Inability to comply with study procedures.
- •History of allergic reactions to study materials.
- •Medical conditions interfering with pain reporting accuracy (pain disorders, constant use of analgesics, anti-inflammatory, or psychotropic medications).
- •History of periodontal surgeries within the last six months.
- •Periodontitis and pulpitis.
研究组 & 干预措施
Group A - Diode Laser + CPP-ACPF
Participants will receive diode laser treatment combined with CPP-ACPF varnish on sensitive teeth.
干预措施: Diode laser photobiomodulation combined with CPP-ACPF varnish (Device)
Group B - CPP-ACPF Varnish Alone
Participants will receive CPP-ACPF varnish alone on sensitive teeth.
干预措施: CPP-ACPF varnish (Other)
结局指标
主要结局
Reduction in dentin hypersensitivity in response to evaporative (air-blast) stimulus
时间窗: Assessed at baseline, immediately post-treatment, and at 1 month, 3 months, and 6 months follow-up.
Change in dentin hypersensitivity in response to an evaporative (air-blast) stimulus, measured using a visual analog scale (VAS). Lower scores indicate reduced sensitivity. Scores: 0-10 (Ordinal) where 0 represents "no pain" and 10 represents "greatest pain".
次要结局
- Reduction in dentin hypersensitivity in response to tactile (dental probe) stimulus.(Assessed at baseline, immediately post-treatment, and at 1 month, 3 months, and 6 months follow-up.)
研究者
Mariam Mamdouh Mohamed Kamal
Dentist
Cairo University